Physiological Profiling
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LOD threshold (Thrd) for Parametric analysis is 2.8 or 2.5 (in a few specific cases). LOD threshold (Thrd) for Non_parametric analysis is 3.5. One phenotype can be mapped on different chromosomes. Group g1 through g18 and phen-group refer to ordering and grouping of phenotypes
No.	Phen. group	Phen. grp. #	Phen. name	Phen. Description	Chr#	Thrd	LOD Peak	Marker
1	EXCR	g7	RF_LS_URINE_NA	sodium concentration of urine, low salt diet following Lasix	1	2.8	4.643	D1Mgh3
2	EXCR	g7	TR_RF_LS_24HR_EXCR_K_LN	potassium excretion rate, low salt diet following Lasix	1	2.8	4.66	D1Mit10
3	EXCR	g7	TR_RF_LS_URINE_K_LN	potassium concentration of urine, low salt diet following Lasix	1	2.8	4.589	D1Mit10
4	BP SD	g10	TR_BPX_HSACTIVEMAPSD_LN	Mean arterial pressure standard deviation, arterial catheter implanted, high salt diet, average of 3 hours collection time, active state - lights off and rat awake	1	2.8	3.836	D1Mit2
5	BP SD	g10	BPX_HSACTIVEDIASD	Diastolic blood pressure standard deviation, arterial catheter implanted, high salt diet, average of 3 hours collection time, active state - lights off and rat awake	1	3.5	3.60022	D1Mit3
6	BP SD	g10	RAWBP_DAY3_SAPSD	Systolic blood pressure standard deviation, High salt, day 3, mean of 3 hour blood pressure recording	1	3.5	3.71601	D1Mit2
7	BP DRUG	g12	ARVA_LS_PRE_NE_MAP_MEAN	Control mean arterial pressure after AngII but before Norepi, anesthetized rat, mean of last two steady state minutes of control period	1	2.8	3.127	D1Mit18
8	NEUROENDOCRINE	g13	BW_LS_PLASMA_RENIN	Plasma renin, low salt diet following Lasix	1	2.8	4.467	D1Mit10
9	HR	g14	DELTA_WAKE_M_DAY2AM_HR	heart rate, high salt diet, p.m. active state value minus a.m. basal state (mean of 3 hours recording each)	1	2.8	2.973	D1Mgh7
10	LIPIDS	g16	BW_TOTAL_CHOLESTEROL_VALUE	Plasma total cholesterol value, low salt diet following Lasix	1	2.8	3.013	D1Mgh7

BioInformatics Research Center Medical College of Wisconsin Email:zwang@mcw.edu Web:http://brc.mcw.edu/