Physiological Profiling
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LOD threshold (Thrd) for Parametric analysis is 2.8 or 2.5 (in a few specific cases). LOD threshold (Thrd) for Non_parametric analysis is 3.5. One phenotype can be mapped on different chromosomes. Group g1 through g18 and phen-group refer to ordering and grouping of phenotypes
No.	Phen. group	Phen. grp. #	Phen. name	Phen. Description	Chr#	Thrd	LOD Peak	Marker
1	RVR NE	g2	TR_D_NE1_M_CTRL_RVR_LN	Delta renal vascular resistance from Norepinephrine dose 1 minus control renal vascular resistance	10	2.8	3.873	D10Mgh11
2	BP DRUG	g12	ARVA_LS_ACH_1_MAP_MEAN	Acetylcholine dose 1 (0.095 ug/kg/min), Mean arterial pressure, anesthetized rat, mean of last two steady state minutes of period	10	2.5	2.504	D10Mgh14
3	BP DRUG	g12	ARVA_LS_ACH_D2_MAP_MEAN	Acetylcholine dose 2 (0.19 ug/kg/min), Mean arterial pressure, anesthetized rat, mean of last two steady state minutes of period	10	2.5	2.792	D10Mgh23
4	MORPHO	g17	AP_HEART_WGHT	heart weight in grams	10	3.5	3.84606	D10Mgh23

BioInformatics Research Center Medical College of Wisconsin Email:zwang@mcw.edu Web:http://brc.mcw.edu/