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| Physiological Profiling | |
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LOD threshold (Thrd) for Parametric analysis is 2.8 or 2.5 (in a few specific cases). LOD threshold (Thrd) for Non_parametric analysis is 3.5. One phenotype can be mapped on different chromosomes. Group g1 through g18 and phen-group refer to ordering and grouping of phenotypes | ||||||||
| No. | Phen. group | Phen. grp. # | Phen. name | Phen. Description | Chr# | Thrd | LOD Peak | Marker |
| 1 | BP SD | g10 | TR_BPX_LSBASALDIASD_SQT | Diastolic blood pressure standard deviation, arterial catheter implanted, low salt diet following Lasix, 3 hours collection time one day, basal state - lights on and rat asleep, | 13 | 2.8 | 2.98 | D13Mgh18 |
| 2 | BP T-SERIES | g11 | BPTSM_TAM_ADA | Tuesday a.m. Exponential scaling factor, baro-receptor response (mechanistic model) | 13 | 3.5 | 3.72886 | D13Mit4 |
| 3 | BP DRUG | g12 | DELTA_ANG3_M_CTRL_BP | Delta mean arterial pressure from AngII dose 3 minus control mean arterial pressure | 13 | 2.8 | 2.944 | D13Mgh4 |
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BioInformatics Research Center Medical College of Wisconsin Email:zwang@mcw.edu Web:http://brc.mcw.edu/ |