Physiological Profiling
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LOD threshold (Thrd) for Parametric analysis is 2.8 or 2.5 (in a few specific cases).
LOD threshold (Thrd) for Non_parametric analysis is 3.5.
One phenotype can be mapped on different chromosomes.
Group g1 through g18 and phen-group refer to ordering and grouping of phenotypes
No. Phen. group Phen. grp. # Phen. name Phen. Description Chr# Thrd LOD Peak Marker
1KID FUNCg8TR_RF_HS_24HR_EXCR_PROTEIN_LNprotein excretion rate, high salt diet182.82.981D18Mgh9
2KID FUNCg8TR_RF_HS_EXCR_PROT_MG24HR_LNprotein excretion rate, high salt diet182.82.933D18Mgh7
3BPg9RAWBP_DAY1_MAPmean blood pressure, High salt, day 1, mean of 3 hour blood pressure recording183.53.53873D18Rat57
4BPg9RAWBP_DAY2_DAPDiastolic blood pressure, High salt, day 2, mean of 3 hour blood pressure recording182.82.829D18Rat57
5BPg9RAWBP_DAY2_MAPmean blood pressure, High salt, day 2, mean of 3 hour blood pressure recording183.54.41065D18Rat57
6BPg9TR_BPX_HSACTIVEDIAMEAN_LNDiastolic blood pressure, arterial catheter implanted, high salt diet, average of 3 hours collection time, active state - lights off and rat awake 182.52.791D18Rat57
7BPg9BPX_HSBASALMAPMEANMean arterial blood pressure, arterial catheter implanted, high salt diet, mean of best 2 out of 3 days, 3 hours collection time per day, basal state - lights on and rat asleep, 183.53.88752D18Rat57
8BPg9BPX_HSACTIVEMAPMEANMean arterial pressure, arterial catheter implanted, high salt diet, average of 3 hours collection time, active state - lights off and rat awake 183.54.36484D18Rat57
9BPg9DELTA_HS_M_LS_MAPBPmean arterial pressure, high salt minus low salt, basal state - lights on and rat asleep183.54.61609D18Rat57
10BPg9DELTA_HS_M_LS_SYSBPSystolic blood pressure, high salt minus low salt, basal state - lights on and rat asleep182.83.643D18Mit3
11BP SDg10RAWBP_DAY2_DAPSDDiastolic blood pressure standard deviation, High salt, day 2, mean of 3 hour blood pressure recording183.53.59112D18Rat57
12BP SDg10RAWBP_DAY2_MAPSDmean blood pressure standard deviation, High salt, day 2, mean of 3 hour blood pressure recording183.53.97196D18Rat57
13BP T-SERIESg11BPTSM_TPM_ALPHA2Tuesday p.m. Linear term 1st order parameter (mechanistic model)182.83.807D18Mgh3
BP T-SERIESg11BPTSM_TPM_ALPHA2Tuesday p.m. Linear term 1st order parameter (mechanistic model)182.83.201D18Mgh9
14BP T-SERIESg11BPTSM_WAM_ALPHA2Wednesday a.m. Linear term 1st order parameter (mechanistic model)182.83.022D18Mgh7
15BP T-SERIESg11BPTSM_WAM_XBARWednesday a.m. Set point for baro-receptor response (mechanistic model)182.83.053D18Rat57
16BP T-SERIESg11TR_BPTSM_TAM_MEAN_LNTuesday a.m. mean blood pressure182.83.269D18Rat57
17LIPIDSg16BW_HDL_VALUEPlasma HDL value, low salt diet following Lasix182.83.826D18Mit8
LIPIDSg16BW_HDL_VALUEPlasma HDL value, low salt diet following Lasix182.83.995D18Mgh7
18MORPHOg17ARVA_WGHTCSBody weight prior to anesthesia for acute protocol 182.82.963D18Mit8