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| Physiological Profiling | |
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LOD threshold (Thrd) for Parametric analysis is 2.8 or 2.5 (in a few specific cases). LOD threshold (Thrd) for Non_parametric analysis is 3.5. One phenotype can be mapped on different chromosomes. Group g1 through g18 and phen-group refer to ordering and grouping of phenotypes | ||||||||
| No. | Phen. group | Phen. grp. # | Phen. name | Phen. Description | Chr# | Thrd | LOD Peak | Marker |
| 1 | RBF ACH | g6 | DELTA_ACH4_M_LNAME_RBF | Delta renal blood flow from Acetylcholine dose 4 minus L-NAME renal blood flow | 3 | 2.8 | 2.814 | D3Rat116 |
| 2 | RBF ACH | g6 | DELTA_ACH4_M_LNAME_RBFK | Delta renal blood flow per gram kidney weight from Acetylcholine dose 4 minus L-NAME renal blood flow per gram kidney weight | 3 | 2.8 | 2.895 | D3Rat116 |
| 3 | EXCR | g7 | TR_RF_LS_URINE_K_LN | potassium concentration of urine, low salt diet following Lasix | 3 | 2.8 | 3.708 | D3Mgh6 |
| 4 | BP SD | g10 | DELTA_HS_M_LS_MAPSD | mean arterial pressure standard deviation , high salt minus low salt, basal state - lights on and rat asleep | 3 | 2.8 | 2.848 | D3Mit4 |
| 5 | BP DRUG | g12 | DELTA_NE3_M_CTRL_BP | Delta mean arterial pressure from Norepinephrine dose 3 minus control mean arterial pressure | 3 | 2.8 | 3.129 | D3Mgh18 |
| 6 | MORPHO | g17 | ARVA_WGHTCS | Body weight prior to anesthesia for acute protocol | 3 | 2.8 | 3.503 | D3Mgh6 |
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BioInformatics Research Center Medical College of Wisconsin Email:zwang@mcw.edu Web:http://brc.mcw.edu/ |