Physiological Profiling
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LOD threshold (Thrd) for Parametric analysis is 2.8 or 2.5 (in a few specific cases).
LOD threshold (Thrd) for Non_parametric analysis is 3.5.
One phenotype can be mapped on different chromosomes.
Group g1 through g18 and phen-group refer to ordering and grouping of phenotypes
No. Phen. group Phen. grp. # Phen. name Phen. Description Chr# Thrd LOD Peak Marker
1KID FUNCg8AP_RGHT_KIDNEY_WGHTright kidney weight72.83.934D7Mit14
2KID FUNCg8AP_LFT_KIDNEY_WGHTleft kidney weight73.54.62096D7Mit14
3BP SDg10DELTA_HS_M_LS_MAPSDmean arterial pressure standard deviation , high salt minus low salt, basal state - lights on and rat asleep72.82.825D7Rat135
4BP T-SERIESg11BPTSM_TAM_ALPHA1Tuesday a.m. Linear term 0th order parameter (mechanistic model)72.84.043D7Mit10
5BP DRUGg12DELTA_ANG1_M_CTRL_BPDelta mean arterial pressure from AngII dose 1 minus control mean arterial pressure72.82.851D7Mit10
6MORPHOg17RF_DELTA_WGHTChange in body weight between day of catheter surgery and day of Lasix injection72.83.348D7Rat135